Using SimBiology for Mechanism-Based PK/PD Modeling in Preclinical & Discovery

Version 1.1.0.1 (55,7 ko) par Fulden Buyukozturk
Examples used in the March 2012 webinar: Using SimBiology for Mechanism-Based PK/PD Modeling
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View the recorded webinar here:
http://www.mathworks.com/videos/using-simbiology-for-mechanism-based-pkpd-modeling-in-preclinical-discovery-81851.html
In this webinar, you learn how to use SimBiology and MATLAB to implement mechanism-based PK/PD modeling workflows. Using a modeling and simulation case-study from literature, we demonstrate:

• Building mechanism-based PK/PD models using an interactive block-diagram editor
• Estimating parameters by fitting experimental data
• Simulating different dosing strategies
• Exploring system dynamics using parameter sweeps & sensitivity analysis
• Automating and customizing analyses using MATLAB

We also highlight new features in SimBiology 2012a including:

• Simulation Viewer – a interactive visualization tool for model exploration
• Weighted fitting
• Simultaneously fitting data from multiple dose levels

Citation pour cette source

Fulden Buyukozturk (2024). Using SimBiology for Mechanism-Based PK/PD Modeling in Preclinical & Discovery (https://www.mathworks.com/matlabcentral/fileexchange/35995-using-simbiology-for-mechanism-based-pk-pd-modeling-in-preclinical-discovery), MATLAB Central File Exchange. Récupéré le .

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En savoir plus sur QSP, PKPD, and Systems Biology dans Help Center et MATLAB Answers
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1.1.0.1

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