SimBiology Tutorials for QSP, PBPK, and PK/PD Modeling and Analysis
SimBiology provides apps and programmatic tools to model, simulate, and analyze dynamic systems, focusing on quantitative systems pharmacology (QSP), physiologically-based pharmacokinetics (PBPK), and pharmacokinetics/pharmacodynamics (PK/PD) applications. The videos in this series walk you through how to use SimBiology and perform common tasks.
Building a Model – Differential Equations Learn how to define differential equations with SimBiology using the Model Builder app.
Building a Model – Algebraic Equations Learn how to define algebraic equations with SimBiology of the Model Builder app.
Simulating a Model in SimBiology This video demonstrates how to simulate a model in SimBiology in the SimBiology Model Analyzer App.
Stratifying Data for Visualization in SimBiology Learn how to use the Model Analyzer app in SimBiology to easily slice or stratify your experimental data and visualize simulation results.
Generating Simulation Scenarios by Sampling Model Quantities Learn how to sample model quantities such as parameters and initial concentrations, dosing schedules, and parameter variants.
Importing Data and Noncompartmental Analysis Importing Data and Noncompartmental Analysis video: Import data from spreadsheets into SimBiology and perform noncompartmental analysis (NCA).
Estimating Parameters (Fixed Effects) Estimating Parameters (Fixed Effects) video: Perform fixed effects parameter estimation, visualize fit results and compare multiple fits
Estimating Parameters (Mixed Effects) Estimating Parameters (Mixed Effects) video: Perform mixed effects parameter estimation
Sampling Parameters from Covariate Models in SimBiology Learn how to sample parameter values from covariate models in SimBiology.