Organising data for confidence intervals

Hi all,
I need to calculate confidence intervals for some parameters i estimated. i did a global partameter estimation and so got 8 parameters. i have 7 data and the 7 seven corresponding simulated sets and three experiments. each experiment has its own sets with differing numbers of discrete time points. i need to build a covarience matrix in order to get the confidence intervals.
anyone know how i can arrange my data to do this?

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