How does SimBiology calculate the "lambda" in NCA?

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Seokuee Kim
Seokuee Kim le 16 Oct 2018
Commenté : Seokuee Kim le 16 Oct 2018
I was wonder that How does SimBiology calculate the "lambda" in NCA?
When I use WinNonlin, I can choice the weighting option in linear regression (ex. unweighted, 1/y, 1/y^2).
Although SimBiology doesn't provide the weighting option, I think that Simbiology uses any one of above.
Thank you.

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Arthur Goldsipe
Arthur Goldsipe le 16 Oct 2018
Hi,
Currently (as of R2018b), SimBiology's NCA uses linear regression with all of the points weighted equally. I'm guessing that's what you would call "unweighted."
-Arthur
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Seokuee Kim
Seokuee Kim le 16 Oct 2018
Thank you for your prompt answer!!

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