how can I read excel data with autofill option from any folder from my pc?

excel = actxserver('Excel.Application');

f = fullfile('c:\','users','user name','desktop';'matlab files')

[Guillaume]

What has autofill got to do with reading excel files?

There is no reason to use excel COM interface (actxserver) just to read data from an excel file. Unless you're familiar with excel VBA, you're better off not using that interface.

[Ashwini More]

actually I want some more calculations in excel and draw the graph using matlab code. I want to standardise and automate this procedure for repetative work

[Guillaume]

I'm confused about your question. What it is you want to do in matlab?