How can I write a 4 dimensional Tiff from a 4D matrix?

I'm trying to convert 4d matrix (XYCZ) into a Tiff that will have also have the required metadata information such as the voxel resolution. I've tried looking at functions such as bfsave, from the bio-formats group but the file size is 4 times bigger (as well as generating issues when trying to apply the original metadata - extracted from bfopen - to the 4d matrix). Is there a faster way?

Ultimately I'm trying to generate an image that can be read by standard microscopy software such as Neurolucida, and FIJI/ImageJ

Thanks in advance,

Marcus

[Walter Roberson]

If I understand correctly, ImageJ cannot read 4D tiff files. Instead it reads 3d tiff sequences with the help of some metadata.

[Marcus Leiwe]

Thanks Walter,

Using the bioformats io plugin you are able to open it as a hyperstack. But as you said it does rely on the metadata. However, I'm having trouble correctly applying the metadata from the original image onto the image I've transformed in MATLAB.

[Martin Privat]

https://fr.mathworks.com/matlabcentral/answers/389765-how-can-i-save-an-image-with-four-channels-or-more-into-an-imagej-compatible-tiff-format#answer_438003