As we know CLA is a 32-bit floating point math accelerator. So any part of the algorithm that involves Math based computation can be implemented on CLA. This would run in parallel with CPU and helps increase the overall bandwidth of the CPU.
Use CLA if the same computation when done on CPU would significantly impact your system performance as CPU in general would handle periodic tasks, events and interrupts. So the choice depends on how much bandwidth you need on the CPU including current and future enhancements.
If your processing on CPU is overrunning on your tasks, then use CLA to offload CPU.