Mixed-effect regression with repeated measures
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I am trying to regress a continuous brain anatomy measure with a behavioral parameter while accounting for age and sex effect. The difficulty I am facing is that I have for each subject two anatomical measures, one for each hemisphere:
Subject Anatomy measure Hemisphere Age Sex Behavior
1 1.2 1 22 2 16,2
1 1.5 2 22 2 16,2
2 1.7 1 25 1 19,3
2 1.8 2 25 1 19,3
How can perform the regression anatomy*behavior while taking into account this repeated measure problem ? I thought that the appropriate way to do that was to perform a linear mixed-effect regression with subjects as a fixed factor. However I am not sure this is a good solution. Does anyone know a function that would deal with repeated measure design for linear regression ?
Thanks in advance !
Peng Li on 6 Aug 2020
This is also an old post now. I guess what the author of this post meant to use subject as a random effect, not a fixed effect, so that the within subject correaltion would be properly taken care of. For me I think that's the way we do it.