Bispecific Protein Degrader PK-PD Model for SimBiology

SimBiology project file for a published PK-PD model for bispecific protein degraders
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Mise à jour 31 mai 2023

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The SimBiology model described in the following publication:
Bartlett DW, Gilbert AM. A kinetic proofreading model for bispecific protein degraders. J Pharmacokinet Pharmacodyn. 2021;48(1):149-163. doi:10.1007/s10928-020-09722-z
Please note that some of the included visualizations require the "gridfit" routine written by John D'Errico: Surface Fitting using gridfit (https://www.mathworks.com/matlabcentral/fileexchange/8998-surface-fitting-using-gridfit), MATLAB Central File Exchange.

Citation pour cette source

Bartlett DW, Gilbert AM. A kinetic proofreading model for bispecific protein degraders. J Pharmacokinet Pharmacodyn. 2021;48(1):149-163. doi:10.1007/s10928-020-09722-z

Compatibilité avec les versions de MATLAB
Créé avec R2022a
Compatible avec les versions R2022a et ultérieures
Plateformes compatibles
Windows macOS Linux
Communautés
Autres fichiers de la communauté  SimBiology

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Version Publié le Notes de version
1.0.2

Modified for compatibility with SimBiology R2022a and newer. The initial release version 1.0.0 was created with SimBiology R2018b and will give errors in the custom visualization programs when run in newer versions of SimBiology.

1.0.1

Modified for compatibility with SimBiology R2022a and newer. The initial release version 1.0.0 was created with SimBiology R2018b and will give errors in the custom visualization programs when run in newer versions of SimBiology.

1.0.0